CATH Domain 2wk5A02

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1030	Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2
	3.40.1030.10	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain

Superfamily	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family	Pyrimidine-nucleoside phosphorylase

2.4.2.4

Thymidine phosphorylase.

based on mapping to UniProt P19971

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.

-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.

TYPH_HUMAN

Homo sapiens

Thymidine phosphorylase

PDB	2WK5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil. Mitsiki, E., Papageorgiou, A.C., Iyer, S., Thiyagarajan, N., Prior, S.H., Sleep, D., Finnis, C., Acharya, K.R. Biochem.Biophys.Res.Commun.