CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Glutathione peroxidase

Enzyme Information

1.11.1.9
Glutathione peroxidase.
based on mapping to UniProt Q00277
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
-!- Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).

UniProtKB Entries (1)

Q00277
GPX1_SCHMA
Schistosoma mansoni
Glutathione peroxidase

PDB Structure

PDB 2WGR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Combining Crystallography and Molecular Dynamics: The Case of Schistosoma Mansoni Phospholipid Glutathione Peroxidase.
Dimastrogiovanni, D., Anselmi, M., Miele, A.E., Boumis, G., Petersson, L., Angelucci, F., Nola, A.D., Brunori, M., Bellelli, A.
Proteins
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