CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.240 | Putative phosphatase; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Putative phosphatase; domain 2 |
| Functional Family | Beta-phosphoglucomutase |
Enzyme Information
| 5.4.2.6 |
Beta-phosphoglucomutase.
based on mapping to UniProt P71447
Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.
-!- The enzyme is able to autophosphorylate itself with its substrate beta-D-glucose 1-phosphate. -!- Although this is a slow reaction, only a single turnover is required for activation. -!- Once the phosphorylated enzyme is formed, it generates the reaction intermediate beta-D-glucose 1,6-bisphosphate, which can be used to phosphorylate the enzyme in subsequent cycles. -!- Cf. EC 5.4.2.2.
|
UniProtKB Entries (1)
| P71447 |
PGMB_LACLA
Lactococcus lactis subsp. lactis Il1403
Beta-phosphoglucomutase
|
PDB Structure
| PDB | 2WF5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Proc. Natl. Acad. Sci. U.S.A.
|
