CATH Domain 2wc3A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.80	Glycosidases

Domain Context

CATH Clusters

Superfamily	Glycosidases
Functional Family	Beta-glucosidase 6-phospho-beta-glucosidase

Enzyme Information

3.2.1.21

Beta-glucosidase.

based on mapping to UniProt Q08638

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

-!- Wide specificity for beta-D-glucosides. -!- Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides.

UniProtKB Entries (1)

Q08638

BGLA_THEMA

Thermotoga maritima MSB8

Beta-glucosidase A

PDB Structure

PDB	2WC3
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Glycosidase Inhibition by Ring-Modified Castanospermine Analogues: Tackling Enzyme Selectivity by Inhibitor Tailoring. Aguilar-Moncayo, M., Gloster, T.M., Turkenburg, J.P., Garcia-Moreno, M.I., Ortiz Mellet, C., Davies, G.J., Garcia Fernandez, J.M. Org.Biomol.Chem.