CATH Domain 2wbbA02

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.190	D-Maltodextrin-Binding Protein; domain 2
	3.40.190.80

Superfamily	3.40.190.80
Functional Family	Fructose-1,6-bisphosphatase class 1

3.1.3.11

Fructose-bisphosphatase.

based on mapping to UniProt P09467

D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.

-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

F16P1_HUMAN

Homo sapiens

Fructose-1,6-bisphosphatase 1

PDB	2WBB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Sulfonylureido Thiazoles as Fructose-1,6-Bisphosphatase Inhibitors for the Treatment of Type-2 Diabetes. Kitas, E., Mohr, P., Kuhn, B., Wessel, H.P., Hebeisen, P., Haap, W., Ruf, A., Benz, J., Joseph, C., Huber, W., Alvarez Sanchez, R., Paehler, A., Bernadeau, A., Gubler, M., Schott, B., Tozzo, E. Bioorg.Med.Chem.Lett.