CATH Domain 2wa5A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.418	Actin-binding Protein, T-fimbrin; domain 1
	1.10.418.10	Calponin-like domain

Domain Context

CATH Clusters

Superfamily	Calponin-like domain
Functional Family	Filamin-B isoform A

Enzyme Information

UniProtKB Entries (1)

FLNB_HUMAN

Homo sapiens

Filamin-B

PDB Structure

PDB	2WA5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Disease-Associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains. Sawyer, G.M., Clark, A.R., Robertson, S.P., Sutherland-Smith, A.J. J.Mol.Biol.