CATH Domain 2w9eA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.790	Major Prion Protein
	1.10.790.10	Prion/Doppel protein, beta-ribbon domain

Domain Context

CATH Clusters

Superfamily	Prion/Doppel protein, beta-ribbon domain
Functional Family	Major prion protein

Enzyme Information

UniProtKB Entries (1)

PRIO_HUMAN

Homo sapiens

Major prion protein

PDB Structure

PDB	2W9E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody. Antonyuk, S.V., Trevitt, C.R., Strange, R.W., Jackson, G.S., Sangar, D., Batchelor, M., Cooper, S., Fraser, C., Jones, S., Georgiou, T., Khalili-Shirazi, A., Clarke, A.R., Hasnain, S.S., Collinge, J. Proc.Natl.Acad.Sci.USA