CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.200 | Phosphorylase Kinase; domain 1 |
|
3.30.200.20 | Phosphorylase Kinase; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphorylase Kinase; domain 1 |
| Functional Family | Calcium/calmodulin-dependent protein kinase type II subunit delta isoform 2 |
Enzyme Information
| 2.7.11.17 |
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q9UQM7
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.
|
UniProtKB Entries (1)
| Q9UQM7 |
KCC2A_HUMAN
Homo sapiens
Calcium/calmodulin-dependent protein kinase type II subunit alpha
|
PDB Structure
| PDB | 2VZ6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.
Plos Biol.
|