CATH Domain 2vwcA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

HSP82_YEAST

Saccharomyces cerevisiae S288C

ATP-dependent molecular chaperone HSP82

PDB Structure

PDB	2VWC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Molecular Characterisation of Macbecin as an Hsp90 Inhibitor Martin, C.J., Gaisser, S., Challis, I.R., Carletti, I., Wilkinson, B., Gregory, M., Prodromou, C., Roe, S.M., Pearl, L.H., Boyd, S.M., Zhang, M.Q. J.Med.Chem.