CATH Domain 2vw5A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.565	Heat Shock Protein 90
	3.30.565.10	Histidine kinase-like ATPase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Histidine kinase-like ATPase, C-terminal domain
Functional Family	Heat shock protein HSP 90-alpha

Enzyme Information

UniProtKB Entries (1)

HSP82_YEAST

Saccharomyces cerevisiae S288C

ATP-dependent molecular chaperone HSP82

PDB Structure

PDB	2VW5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Optimizing Natural Products by Biosynthetic Engineering: Discovery of Nonquinone Hsp90 Inhibitors. Zhang, M.Q., Gaisser, S., Nur-E-Alam, M., Sheehan, L.S., Vousden, W.A., Gaitatzis, N., Peck, G., Coates, N.J., Moss, S.J., Radzom, M., Foster, T.A., Sheridan, R.M., Gregory, M.A., Roe, S.M., Prodromou, C., Pearl, L.H., Boyd, S.M., Wilkinson, B., Martin, C.J. J.Med.Chem.