CATH Domain 2vhxD01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	Alanine dehydrogenase

Enzyme Information

1.4.1.1

Alanine dehydrogenase.

based on mapping to UniProt P9WQB1

L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH.

UniProtKB Entries (1)

DHA_MYCTU

Mycobacterium tuberculosis H37Rv

Alanine dehydrogenase

PDB Structure

PDB	2VHX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding. Agren, D., Stehr, M., Berthold, C.L., Kapoor, S., Oehlmann, W., Singh, M., Schneider, G. J.Mol.Biol.