CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.230.10
Functional Family

Enzyme Information

2.7.1.148
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase.
based on mapping to UniProt O67060
ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

O67060
ISPE_AQUAE
Aquifex aeolicus VF5
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

PDB Structure

PDB 2V34
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterization of Aquifex Aeolicus 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase -Ligand Recognition in a Template for Antimicrobial Drug Discovery.
Sgraja, T., Alphey, M.S., Ghilagaber, S., Marquez, R., Robertson, M.N., Hemmings, J.L., Lauw, S., Rohdich, F., Bacher, A., Eisenreich, W., Illarionova, V., Hunter, W.N.
FEBS J.
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