CATH Domain 2uz9A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.140	Metal-dependent hydrolases

Domain Context

CATH Clusters

Superfamily	Metal-dependent hydrolases
Functional Family	Guanine deaminase

Enzyme Information

3.5.4.3

Guanine deaminase.

based on mapping to UniProt Q9Y2T3

Guanine + H(2)O = xanthine + NH(3).

UniProtKB Entries (1)

GUAD_HUMAN

Homo sapiens

Guanine deaminase

PDB Structure

PDB	2UZ9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Human Guanine Deaminase (Guad) in Complex with Zinc and its Product Xhantine Moche, M., Welin, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P. To be Published