CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
6 | Special |
|
6.10 | Helix non-globular |
|
6.10.250 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
6.10.250.2970 |
Domain Context
CATH Clusters
| Superfamily | 6.10.250.2970 |
| Functional Family |
Enzyme Information
| 5.2.1.8 |
Peptidylprolyl isomerase.
based on mapping to UniProt Q5ZXE0
Peptidylproline (omega=180) = peptidylproline (omega=0).
-!- The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A. -!- Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli. -!- The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively.
|
UniProtKB Entries (1)
| Q5ZXE0 |
MIP_LEGPH
Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Outer membrane protein MIP
|
PDB Structure
| PDB | 2UZ5 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Domain Motions of the Mip Protein from Legionella Pneumophila
Biochemistry
|