CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family

Enzyme Information

4.2.2.15
Anhydrosialidase.
based on mapping to UniProt Q27701
Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.
-!- Also acts on N-glycolylneuraminate glycosides. -!- Cf. EC 3.2.1.18 and EC 3.2.1.129. -!- Formerly EC 3.2.1.138.

UniProtKB Entries (1)

Q27701
NANL_MACDE
Macrobdella decora
Anhydrosialidase

PDB Structure

PDB 2SLI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The 1.8 A structures of leech intramolecular trans-sialidase complexes: evidence of its enzymatic mechanism.
Luo, Y., Li, S.C., Li, Y.T., Luo, M.
J.Mol.Biol.
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