CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.450 | Nuclear Transport Factor 2; Chain: A, |
|
3.10.450.60 |
Domain Context
CATH Clusters
| Superfamily | 3.10.450.60 |
| Functional Family |
Enzyme Information
| 1.13.11.12 |
Linoleate 13S-lipoxygenase.
based on mapping to UniProt P08170
(1) Linoleate + O(2) = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate. (2) Alpha-linolenate + O(2) = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca- 9,11,15-trienoate.
-!- A common plant lipoxygenase that oxidizes linoleate and alpha- linolenate, the two most common polyunsaturated fatty acids in plants, by inserting molecular oxygen at the C(13) position with (S)- configuration. -!- This enzyme produces precursors for several important compounds, including the plant hormone jasmonic acid. -!- EC 1.13.11.58 catalyzes a similar reaction at the second available position of these fatty acids. -!- Formerly EC 1.13.1.13 and EC 1.99.2.1.
|
UniProtKB Entries (1)
| P08170 |
LOX1_SOYBN
Glycine max
Seed linoleate 13S-lipoxygenase-1
|
PDB Structure
| PDB | 2SBL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The three-dimensional structure of an arachidonic acid 15-lipoxygenase.
Science
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