CATH Classification

Domain Context

CATH Clusters

Superfamily Cytochrome P450
Functional Family Cytochrome P450 monooxygenase

Enzyme Information

1.7.1.14
Nitric oxide reductase (NAD(P)(+), nitrous oxide-forming).
based on mapping to UniProt P23295
Nitrous oxide + NAD(P)(+) + H(2)O = 2 nitric oxide + NAD(P)H.
-!- The enzyme from Fusarium oxysporum utilizes only NADH, but the isozyme from Trichosporon cutaneum utilizes both NADH and NADPH. -!- The electron transfer from NAD(P)H to heme occurs directly, not requiring flavin or other redox cofactors.

UniProtKB Entries (1)

P23295
NOR_FUSOX
Fusarium oxysporum
NADP nitrous oxide-forming nitric oxide reductase

PDB Structure

PDB 2ROM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum.
Park, S.Y., Shimizu, H., Adachi, S., Nakagawa, A., Tanaka, I., Nakahara, K., Shoun, H., Obayashi, E., Nakamura, H., Iizuka, T., Shiro, Y.
Nat.Struct.Biol.