CATH Domain 2romA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.630	Cytochrome p450
	1.10.630.10	Cytochrome P450

Domain Context

CATH Clusters

Superfamily	Cytochrome P450
Functional Family	Cytochrome P450 monooxygenase

Enzyme Information

1.7.1.14

Nitric oxide reductase (NAD(P)(+), nitrous oxide-forming).

based on mapping to UniProt P23295

Nitrous oxide + NAD(P)(+) + H(2)O = 2 nitric oxide + NAD(P)H.

-!- The enzyme from Fusarium oxysporum utilizes only NADH, but the isozyme from Trichosporon cutaneum utilizes both NADH and NADPH. -!- The electron transfer from NAD(P)H to heme occurs directly, not requiring flavin or other redox cofactors.

UniProtKB Entries (1)

P23295

NOR_FUSOX

Fusarium oxysporum

NADP nitrous oxide-forming nitric oxide reductase

PDB Structure

PDB	2ROM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum. Park, S.Y., Shimizu, H., Adachi, S., Nakagawa, A., Tanaka, I., Nakahara, K., Shoun, H., Obayashi, E., Nakamura, H., Iizuka, T., Shiro, Y. Nat.Struct.Biol.