CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphoenolpyruvate Carboxykinase, domain 2
Functional Family Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

Enzyme Information

4.1.1.32
Phosphoenolpyruvate carboxykinase (GTP).
based on mapping to UniProt P07379
GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO(2).
-!- ITP can act as phosphate donor.

UniProtKB Entries (1)

P07379
PCKGC_RAT
Rattus norvegicus
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

PDB Structure

PDB 2RKA
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition.
Stiffin, R.M., Sullivan, S.M., Carlson, G.M., Holyoak, T.
Biochemistry