CATH Classification

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family A disintegrin and metalloproteinase with thrombospondin motifs 1

Enzyme Information

3.4.24.-
Metalloendopeptidases.
based on mapping to UniProt Q9UNA0

UniProtKB Entries (1)

Q9UNA0
ATS5_HUMAN
Homo sapiens
A disintegrin and metalloproteinase with thrombospondin motifs 5

PDB Structure

PDB 2RJQ
External Links
Method X-RAY DIFFRACTION
Organism Cricetulus
Primary Citation
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Mosyak, L., Georgiadis, K., Shane, T., Svenson, K., Hebert, T., McDonagh, T., Mackie, S., Olland, S., Lin, L., Zhong, X., Kriz, R., Reifenberg, E.L., Collins-Racie, L.A., Corcoran, C., Freeman, B., Zollner, R., Marvell, T., Vera, M., Sum, P.E., Lavallie, E.R., Stahl, M., Somers, W.
Protein Sci.