CATH Domain 2rhsC00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Phenylalanine--tRNA ligase alpha subunit

Enzyme Information

6.1.1.20

Phenylalanine--tRNA ligase.

based on mapping to UniProt Q4L5E3

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl- tRNA(Phe).

UniProtKB Entries (1)

SYFA_STAHJ

Staphylococcus haemolyticus JCSC1435

Phenylalanine--tRNA ligase alpha subunit

PDB Structure

PDB	2RHS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Rational protein engineering in action: the first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus. Evdokimov, A.G., Mekel, M., Hutchings, K., Narasimhan, L., Holler, T., McGrath, T., Beattie, B., Fauman, E., Yan, C., Heaslet, H., Walter, R., Finzel, B., Ohren, J., McConnell, P., Braden, T., Sun, F., Spessard, C., Banotai, C., Al-Kassim, L., Ma, W., Wengender, P., Kole, D., Garceau, N., Toogood, P., Liu, J. J.Struct.Biol.