CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Guanine nucleotide-binding protein G(q) subunit alpha |
Enzyme Information
UniProtKB Entries (2)
| Q86VW2 |
ARHGP_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 25
|
| P21279 |
GNAQ_MOUSE
Mus musculus
Guanine nucleotide-binding protein G(q) subunit alpha
|
PDB Structure
| PDB | 2RGN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Trichoplusia |
| Primary Citation |
Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs.
Science
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