CATH Classification

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family renin

Enzyme Information

3.4.23.15
Renin.
based on mapping to UniProt P00797
Cleavage of Leu-|-Xaa bond in angiotensinogen to generate angiotensin I.
-!- Belongs to peptidase family A1. -!- Formerly EC 3.4.4.15 and EC 3.4.99.19.

UniProtKB Entries (1)

P00797
RENI_HUMAN
Homo sapiens
Renin

PDB Structure

PDB 2REN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution.
Sielecki, A.R., Hayakawa, K., Fujinaga, M., Murphy, M.E., Fraser, M., Muir, A.K., Carilli, C.T., Lewicki, J.A., Baxter, J.D., James, M.N.
Science
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