CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.1990 | Viral RNA-directed RNA polymerase, 4-helical domain |
Domain Context
CATH Clusters
| Superfamily | Viral RNA-directed RNA polymerase, 4-helical domain |
| Functional Family |
Enzyme Information
| 2.7.7.48 |
RNA-directed RNA polymerase.
based on mapping to UniProt O37061
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.
|
UniProtKB Entries (1)
| O37061 |
RDRP_ROTSP
Simian 11 rotavirus (serotype 3 / strain SA11-Patton)
RNA-directed RNA polymerase
|
PDB Structure
| PDB | 2R7W |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure
|
