CATH Domain 2qx0A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.560	7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK

Domain Context

CATH Clusters

Superfamily	7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK
Functional Family	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

Enzyme Information

UniProtKB Entries (1)

A0A0H2W2M8_YERPE

Yersinia pestis

2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase

PDB Structure

PDB	2QX0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics. Blaszczyk, J., Li, Y., Cherry, S., Alexandratos, J., Wu, Y., Shaw, G., Tropea, J.E., Waugh, D.S., Yan, H., Ji, X. Acta Crystallogr.,Sect.D