CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.200 | Tumour Suppressor Smad4 |
|
2.60.200.40 |
Domain Context
CATH Clusters
| Superfamily | 2.60.200.40 |
| Functional Family | Diacylglycerol kinase |
Enzyme Information
| 2.7.1.107 |
Diacylglycerol kinase (ATP).
based on mapping to UniProt Q6GFF9
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
-!- Involved in synthesis of membrane phospholipids and the neutral lipid triacylglycerol. -!- Activity is stimulated by certain phospholipids. -!- In plants and animals the product 1,2-diacyl-sn-glycerol 3-phosphate is an important second messenger. -!- cf. EC 2.7.1.174.
|
UniProtKB Entries (1)
| Q6GFF9 |
DAGK_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Diacylglycerol kinase
|
PDB Structure
| PDB | 2QVL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Analysis of the Staphylococcus aureus DgkB Structure Reveals a Common Catalytic Mechanism for the Soluble Diacylglycerol Kinases.
Structure
|