CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt Q9Y6K1
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

Q9UJW3
DNM3L_HUMAN
Homo sapiens
DNA (cytosine-5)-methyltransferase 3-like

PDB Structure

PDB 2QRV
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation.
Jia, D., Jurkowska, R.Z., Zhang, X., Jeltsch, A., Cheng, X.
Nature