CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent dethiobiotin synthetase BioD

Enzyme Information

6.3.3.3
Dethiobiotin synthase.
based on mapping to UniProt O24872
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.
-!- CTP has half the activity of ATP.

UniProtKB Entries (1)

O24872
BIOD_HELPY
Helicobacter pylori 26695
ATP-dependent dethiobiotin synthetase BioD

PDB Structure

PDB 2QMO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members.
Porebski, P.J., Klimecka, M., Chruszcz, M., Nicholls, R.A., Murzyn, K., Cuff, M.E., Xu, X., Cymborowski, M., Murshudov, G.N., Savchenko, A., Edwards, A., Minor, W.
Febs J.