CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1280 | Alpha/beta knot |
|
3.40.1280.10 | SPOUT methyltransferase, trefoil knot domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.1280.10 |
| Functional Family |
Enzyme Information
| 2.1.1.257 |
tRNA (pseudouridine(54)-N(1))-methyltransferase.
based on mapping to UniProt O29206
S-adenosyl-L-methionine + pseudouridine(54) in tRNA = S-adenosyl-L- homocysteine + N(1)-methylpseudouridine(54) in tRNA.
-!- While this archaeal enzyme is specific for the 54 position and does not methylate pseudouridine at position 55, the presence of pseudouridine at position 55 is necessary for the efficient methylation of pseudouridine at position 54.
|
UniProtKB Entries (1)
| O29206 |
TRMY_ARCFU
Archaeoglobus fulgidus DSM 4304
TRNA (pseudouridine(54)-N(1))-methyltransferase
|
PDB Structure
| PDB | 2QMM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of APC86534.1 (C-terminal domain of NCBI AAB90184.1; Pfam BIG 123.1).
To be Published
|