CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.150 | Chorismate synthase, AroC fold |
|
3.60.150.10 | Chorismate synthase AroC |
Domain Context
CATH Clusters
| Superfamily | Chorismate synthase AroC |
| Functional Family | Chorismate synthase |
Enzyme Information
| 4.2.3.5 |
Chorismate synthase.
based on mapping to UniProt P9WPY1
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
-!- The reaction goes via a radical mechanism that involves reduced FMN and its semiquinone (FMNH.). -!- Shikimate is numbered so that the double-bond is between C-1 and C-2, but some earlier papers numbered the ring in the reverse direction. -!- Formerly EC 4.6.1.4.
|
UniProtKB Entries (1)
| P9WPY1 |
AROC_MYCTU
Mycobacterium tuberculosis H37Rv
Chorismate synthase
|
PDB Structure
| PDB | 2QHF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mycobacterium tuberculosis Chorismate synthase in complex with NCA
To be Published
|
