CATH Classification

Domain Context

CATH Clusters

Superfamily Nitrile hydratase alpha /Thiocyanate hydrolase gamma
Functional Family

Enzyme Information

4.2.1.84
Nitrile hydratase.
based on mapping to UniProt P13448
An aliphatic amide = a nitrile + H(2)O.
-!- Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. -!- Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).

UniProtKB Entries (1)

P13449
NHAB_RHOER
Rhodococcus erythropolis
Nitrile hydratase subunit beta

PDB Structure

PDB 2QDY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
High resolution X-ray molecular structure of the nitrile hydratase from Rhodococcus erythropolis AJ270 reveals posttranslational oxidation of two cysteines into sulfinic acids and a novel biocatalytic nitrile hydration mechanism
Song, L., Wang, M., Shi, J., Xue, Z., Wang, M.-X., Qian, S.
Biochem.Biophys.Res.Commun.
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