CATH Domain 2q85A03

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.78	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1
	3.90.78.10	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain

Superfamily	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Functional Family	UDP-N-acetylenolpyruvoylglucosamine reductase

1.3.1.98

UDP-N-acetylmuramate dehydrogenase.

based on mapping to UniProt P08373

UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.

-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

MURB_ECOLI

Escherichia coli K-12

UDP-N-acetylenolpyruvoylglucosamine reductase

PDB	2Q85
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of E. Coli Mur B bound to a napthyl tetronic acid inhibitor Mansour, T., Caulfield, C.E., Rasmussen, B., Chopra, R., Krishnamurthy, G., Morris, K.M., Svenson, K., Bard, J., Smeltzer, C., Naughton, S., Antane, S., Yang, Y., Severin, A., Quagliato, D., Petersen, P.J., Singh, G. TO BE PUBLISHED