CATH Domain 2q85A01

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.43	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 2
	3.30.43.10	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2

Superfamily	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family

1.3.1.98

UDP-N-acetylmuramate dehydrogenase.

based on mapping to UniProt P08373

UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.

-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

MURB_ECOLI

Escherichia coli K-12

UDP-N-acetylenolpyruvoylglucosamine reductase

PDB	2Q85
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of E. Coli Mur B bound to a napthyl tetronic acid inhibitor Mansour, T., Caulfield, C.E., Rasmussen, B., Chopra, R., Krishnamurthy, G., Morris, K.M., Svenson, K., Bard, J., Smeltzer, C., Naughton, S., Antane, S., Yang, Y., Severin, A., Quagliato, D., Petersen, P.J., Singh, G. TO BE PUBLISHED