CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1100
Functional Family Cysteine synthase

Enzyme Information

2.5.1.47
Cysteine synthase.
based on mapping to UniProt P9WP55
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.

UniProtKB Entries (1)

P9WP55
CYSK_MYCTU
Mycobacterium tuberculosis H37Rv
O-acetylserine sulfhydrylase

PDB Structure

PDB 2Q3D
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural Insights into Catalysis and Inhibition of O-Acetylserine Sulfhydrylase from Mycobacterium tuberculosis: CRYSTAL STRUCTURES OF THE ENZYME {alpha}-AMINOACRYLATE INTERMEDIATE AND AN ENZYME-INHIBITOR COMPLEX.
Schnell, R., Oehlmann, W., Singh, M., Schneider, G.
J.Biol.Chem.