CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.129 | Thiol Ester Dehydrase; Chain A |
|
3.10.129.10 | Hotdog Thioesterase |
Domain Context
CATH Clusters
| Superfamily | Hotdog Thioesterase |
| Functional Family | Cytosolic acyl coenzyme A thioester hydrolase |
Enzyme Information
| 3.1.2.2 |
Palmitoyl-CoA hydrolase.
based on mapping to UniProt Q91V12
Palmitoyl-CoA + H(2)O = CoA + palmitate.
-!- Also hydrolyzes CoA thioesters of other long-chain fatty acids.
|
UniProtKB Entries (1)
| Q91V12 |
BACH_MOUSE
Mus musculus
Cytosolic acyl coenzyme A thioester hydrolase
|
PDB Structure
| PDB | 2Q2B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation.
Proc.Natl.Acad.Sci.Usa
|
