CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.10 | Roll | |
3.10.330 | Vcp-like ATPase; Chain A, domain 2 | |
3.10.330.40 |
Domain Context
CATH Clusters
Superfamily | 3.10.330.40 |
Functional Family | 2-dehydro-3-deoxy-D-arabinonate dehydratase |
Enzyme Information
4.2.1.141 |
2-dehydro-3-deoxy-D-arabinonate dehydratase.
based on mapping to UniProt Q97UA0
2-dehydro-3-deoxy-D-arabinonate = 2,5-dioxopentanoate + H(2)O.
-!- The enzyme participates in pentose oxidation pathways that convert pentose sugars to the tricarboxylic acid cycle intermediate 2-oxoglutarate.
|
UniProtKB Entries (1)
Q97UA0 |
KDAD_SACS2
Saccharolobus solfataricus P2
2-dehydro-3-deoxy-D-arabinonate dehydratase
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PDB Structure
PDB | 2Q19 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J.Mol.Biol.
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