CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.850 | Fumarylacetoacetate hydrolase; domain 2 |
|
3.90.850.10 | Fumarylacetoacetase-like, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Fumarylacetoacetase-like, C-terminal domain |
| Functional Family | 2-dehydro-3-deoxy-D-arabinonate dehydratase |
Enzyme Information
| 4.2.1.141 |
2-dehydro-3-deoxy-D-arabinonate dehydratase.
based on mapping to UniProt Q97UA0
2-dehydro-3-deoxy-D-arabinonate = 2,5-dioxopentanoate + H(2)O.
-!- The enzyme participates in pentose oxidation pathways that convert pentose sugars to the tricarboxylic acid cycle intermediate 2-oxoglutarate.
|
UniProtKB Entries (1)
| Q97UA0 |
KDAD_SACS2
Saccharolobus solfataricus P2
2-dehydro-3-deoxy-D-arabinonate dehydratase
|
PDB Structure
| PDB | 2Q18 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J.Mol.Biol.
|
