CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.1770 | TPR 1 domain of DNA polymerase |
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3.30.1770.10 | TPR 1 domain of DNA polymerase |
Domain Context
CATH Clusters
Superfamily | TPR 1 domain of DNA polymerase |
Functional Family | DNA polymerase |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P03680
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
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3.1.11.- |
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt P03680
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UniProtKB Entries (1)
P03680 |
DPOL_BPPH2
Bacillus virus phi29
DNA polymerase
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PDB Structure
PDB | 2PYL |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases
Embo J.
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