1 keywords

CATH Domain 2puiA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.1200 Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2
Homologous Superfamily 3.90.1200.10 Aminoglycoside phosphotransferase (APH), C-terminal lobe

Domain Context

CATH Clusters

Superfamily 3.90.1200.10
Functional Family

Enzyme Information

2.7.1.100
S-methyl-5-thioribose kinase.
based on mapping to UniProt O31663
ATP + S-methyl-5-thio-D-ribose = ADP + S-methyl-5-thio-alpha-D-ribose 1-phosphate.
-!- Also acts, more slowly, on CTP.

UniProtKB Entries (1)

O31663
MTNK_BACSU
Bacillus subtilis subsp. subtilis str. 168
Methylthioribose kinase

PDB Structure

PDB 2PUI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding
Ku, S.-Y., Yip, P., Cornell, K.A., Riscoe, M.K., Behr, J.-B., Guillerm, G., Howell, P.L.
J.Biol.Chem.