CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2140 | Arylamine N-acetyltransferase fold |
|
3.30.2140.20 |
Domain Context
CATH Clusters
| Superfamily | 3.30.2140.20 |
| Functional Family | Arylamine N-acetyltransferase 1 |
Enzyme Information
| 2.3.1.5 |
Arylamine N-acetyltransferase.
based on mapping to UniProt P18440
Acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
-!- Wide specificity for aromatic amines, including serotonin; also catalyzes acetyl-transfer between arylamines without CoA.
|
UniProtKB Entries (1)
| P18440 |
ARY1_HUMAN
Homo sapiens
Arylamine N-acetyltransferase 1
|
PDB Structure
| PDB | 2PQT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural Basis of Substrate-binding Specificity of Human Arylamine N-Acetyltransferases.
J.Biol.Chem.
|
