CATH Classification

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family Transcription initiation factor IIB

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q00403
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

P06492
VP16_HHV11
Human alphaherpesvirus 1 strain 17
Tegument protein VP16
Q00403
TF2B_HUMAN
Homo sapiens
Transcription initiation factor IIB

PDB Structure

PDB 2PHG
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structural Properties of the Promiscuous VP16 Activation Domain
Jonker, H.R.A., Wechselberger, R.W., Boelens, R., Folkers, G.E., Kaptein, R.
Biochemistry