CATH Domain 2p59A02

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Superfamily	Trypsin-like serine proteases
Functional Family	Genome polyprotein

P27958	POLG_HCVH Hepatitis C virus (isolate H) Genome polyprotein
Q91RS4	Q91RS4_9HEPC Hepacivirus C NS3 protease

PDB	2P59
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics. Perni, R.B., Chandorkar, G., Cottrell, K.M., Gates, C.A., Lin, C., Lin, K., Luong, Y.P., Maxwell, J.P., Murcko, M.A., Pitlik, J., Rao, G., Schairer, W.C., Van Drie, J., Wei, Y. Bioorg.Med.Chem.Lett.