CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
Superfamily | NAD(P)-binding Rossmann-like Domain |
Functional Family |
Enzyme Information
1.1.1.348 |
(3R)-2'-hydroxyisoflavanone reductase.
based on mapping to UniProt Q40316
A (4R)-4,2'-dihydroxyisoflavan + NADP(+) = a (3R)-2'-hydroxyisoflavanone + NADPH.
-!- This plant enzyme participates in the biosynthesis of the pterocarpan phytoalexins medicarpin, maackiain, and several forms of glyceollin. -!- The enzyme has a strict stereo specificity for the 3R-isoflavanones. -!- Formerly EC 1.1.1.246.
|
UniProtKB Entries (1)
Q40316 |
VESTR_MEDSA
Medicago sativa
Vestitone reductase
|
PDB Structure
PDB | 2P4H |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.).
J.Mol.Biol.
|