CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Lysine-specific demethylase 4A

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O75164

UniProtKB Entries (1)

P68431
H31_HUMAN
Homo sapiens
Histone H3.1

PDB Structure

PDB 2OX0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Ng, S.S., Kavanagh, K.L., McDonough, M.A., Butler, D., Pilka, E.S., Lienard, B.M., Bray, J.E., Savitsky, P., Gileadi, O., von Delft, F., Rose, N.R., Offer, J., Scheinost, J.C., Borowski, T., Sundstrom, M., Schofield, C.J., Oppermann, U.
Nature
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