CATH Domain 2owiA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.167	Regulator of G-protein Signalling 4; domain 2
	1.10.167.10	Regulator of G-protein Signalling 4, domain 2

Domain Context

CATH Clusters

Superfamily	Regulator of G-protein Signalling 4, domain 2
Functional Family	Putative regulator of g-protein signaling 12

Enzyme Information

UniProtKB Entries (1)

RGS18_HUMAN

Homo sapiens

Regulator of G-protein signaling 18

PDB Structure

PDB	2OWI
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Soundararajan, M., Willard, F.S., Kimple, A.J., Turnbull, A.P., Ball, L.J., Schoch, G.A., Gileadi, C., Fedorov, O.Y., Dowler, E.F., Higman, V.A., Hutsell, S.Q., Sundstrom, M., Doyle, D.A., Siderovski, D.P. Proc.Natl.Acad.Sci.Usa