CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.230 | Creatine Amidinohydrolase |
|
3.90.230.10 | Creatinase/methionine aminopeptidase superfamily |
Domain Context
CATH Clusters
| Superfamily | Creatinase/methionine aminopeptidase superfamily |
| Functional Family |
Enzyme Information
| 3.4.13.9 |
Xaa-Pro dipeptidase.
based on mapping to UniProt P12955
Hydrolysis of Xaa-|-Pro dipeptides. Also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro.
-!- Possibly thiol dependent. -!- Cytosolic from most animal tissues. -!- Belongs to peptidase family M24A. -!- Formerly EC 3.4.3.7.
|
UniProtKB Entries (1)
| P12955 |
PEPD_HUMAN
Homo sapiens
Xaa-Pro dipeptidase
|
PDB Structure
| PDB | 2OKN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of Human Prolidase: The Molecular Basis of PD Disease.
To be Published
|
