CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Ornithine aminotransferase |
Enzyme Information
| 2.6.1.13 |
Ornithine aminotransferase.
based on mapping to UniProt P04181
L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
|
UniProtKB Entries (1)
| P04181 |
OAT_HUMAN
Homo sapiens
Ornithine aminotransferase, mitochondrial
|
PDB Structure
| PDB | 2OAT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine.
J.Mol.Biol.
|
