CATH Classification

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Nuclear receptor subfamily 1 group I member 2

Enzyme Information

UniProtKB Entries (2)

P70365
NCOA1_MOUSE
Mus musculus
Nuclear receptor coactivator 1
O75469
NR1I2_HUMAN
Homo sapiens
Nuclear receptor subfamily 1 group I member 2

PDB Structure

PDB 2O9I
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the PXR-T1317 complex provides a scaffold to examine the potential for receptor antagonism.
Xue, Y., Chao, E., Zuercher, W.J., Willson, T.M., Collins, J.L., Redinbo, M.R.
Bioorg.Med.Chem.
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