CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.309 | Aldehyde Dehydrogenase; Chain A, domain 2 |
|
3.40.309.10 | Aldehyde Dehydrogenase; Chain A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Aldehyde Dehydrogenase; Chain A, domain 2 |
| Functional Family | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
Enzyme Information
| 1.5.1.6 |
Formyltetrahydrofolate dehydrogenase.
based on mapping to UniProt P28037
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
|
UniProtKB Entries (1)
| P28037 |
AL1L1_RAT
Rattus norvegicus
Cytosolic 10-formyltetrahydrofolate dehydrogenase
|
PDB Structure
| PDB | 2O2Q |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry
|