CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1240 | Zincin-like |
|
3.90.1240.10 | Metalloproteases ("zincins"), catalytic domain like |
Domain Context
CATH Clusters
| Superfamily | Metalloproteases ("zincins"), catalytic domain like |
| Functional Family | Botulinum neurotoxin type B |
Enzyme Information
| 3.4.24.69 |
Bontoxilysin.
based on mapping to UniProt P10844
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.
|
UniProtKB Entries (2)
| P46097 |
SYT2_MOUSE
Mus musculus
Synaptotagmin-2
|
| P10844 |
BXB_CLOBO
Clostridium botulinum
Botulinum neurotoxin type B
|
PDB Structure
| PDB | 2NP0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
Nature
|
