CATH Domain 2nnxA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.200	Superoxide dismutase, copper/zinc binding domain

Domain Context

CATH Clusters

Superfamily	Superoxide dismutase, copper/zinc binding domain
Functional Family	Superoxide dismutase [Cu-Zn]

Enzyme Information

1.15.1.1

Superoxide dismutase.

based on mapping to UniProt P00441

2 superoxide + 2 H(+) = O(2) + H(2)O(2).

UniProtKB Entries (1)

SODC_HUMAN

Homo sapiens

Superoxide dismutase [Cu-Zn]

PDB Structure

PDB	2NNX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Saccharomyces
Primary Citation	Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability Wang, J., Caruano-Yzermans, A., Rodriguez, A., Scheurmann, J.P., Slunt, H.H., Cao, X., Gitlin, J., Hart, P.J., Borchelt, D.R. J.Biol.Chem.